Wednesday, October 31, 2012

Boduch's Blog: New Computer Users

I can't remember when, or why exactly, I started using a desktop computer. The fact that it was a clunky desktop system running Windows 93 says something all on its own. Clearly, I didn't have any idea how irrelevant that system would become in short order. New computer users don't understand how quickly technology development moves ? if I had known that, I probably wouldn't have bothered. The fact of the matter is that when I first started using a computer, I wasn't a developer, I wasn't using the thing as a tool to do any meaningful work. The real driving force was simple curiosity. That curiosity, I'm sure, was partly driven by the surrounding hype at the time. Computers, and their interconnected fabric were the future. If you didn't understand them and tightly integrate them into every aspect of your daily life, you'd left behind. Back then, I don't think the surrounding hype got the best of me. Hype hasn't slowed down, its simply moved on ? mobile computing for instance. I was too busy doing kid stuff to really appreciate the ramifications, and so I was considered a casual user. Probably like a lot of people around the globe who use computers, but don't depend on them for critical tasks. Then there are other types of users. There are developers, there are non-humans. We can classify users based on why they're currently using a computer, not why they first started.

When I first started using a computer, my perceived notions about the technology were hardware-centric. My interests were based on what I could see ? it's the machine itself that makes things happen. Which makes sense from an educational standpoint. As you're making your way through school, particularly at the younger end, physical objects are the best illustrators of concepts. This is a triangle, the same as the one you're seeing in the book. This is a toy firetruck, the same as the one driving by out on the street. It's much easier to grasp new concepts when they're presented visually, and in my case, the computer itself was responsible for ? whatever it was I thought computers did. From there, you start interacting with objects. It's one thing to see an object in the real world and draw an analogy to a concept formed in your mind. It's a more powerful thing to take a toy broom and start using it the same way the teacher does. The user interface on any computer system is the first thing any new computer user will manipulate if given the chance. This first interaction could make or break that person's lifelong relationship with computer technology. If you have a bad experience, like the first time you play a sport and end up injuring yourself ? you're impression of that experience taints any future variations of it. And so an interface that allows the user to perform actions on it is better than one with limited capabilities. But it goes further than that to include instruction. Whether the interface the first time user is being presented with has many actions, or is restrictive, they need to be discoverable. They need to lead to more inquiries from the user. Well, I can do that, can I do this? That doesn't work, did I do it wrong? Encouragement of deep probing can really suck people in. But not everyone.

If it were true that all was needed to create a successful user interface were instructional simplicity, there wouldn't be nearly as much software in existence as there is today. If you think about it, software, ultimately, is designed for some actor to solve a particular problem they're having. But, if first time users could all pick up how to perform queries, how to issue commands, and how to extend and improve the system at first glance, we wouldn't need all this specialized software that strives to make things easier for a particular class of user. From another point of view, new computer users are embryonic, and once they're exposed to their new computer environment, they develop new skills, attitudes, and ideas that fall outside the realm of computing. Computer use has a cumulative effect over time, and over this time, the knowledge you're building up helps determine your user class. After first starting with a computer, it doesn't take long to figure out that it was a loathsome experience or that it was an important tool and you cannot figure out how you lived without it. But form this point onward, you're no longer a new computer user, you're a software user.

Once you find yourself fitting into a general class of software user, you tend to evolve in a certain direction. Over time, you develop a personal taste for what makes a good application. The use cases you're playing into also determines the trajectory of your software choices. You make some bad calls, your direction changes slightly, toward a different set of software that does mostly the same thing, but maybe it does once small aspect of it better. Or maybe you've found some application that works exactly how you see fit. Maybe this confirms some doubts you've had as a user in your chosen problem domain and you've now further solidified the path you're on. What's interesting is how all this happens. There is such a diverse set of usage patterns out in the software ecosystem that it's very difficult to measure patterns. I'm not talking about the hoards of Mac and Windows users ? I'm talking about the complex configurations that seem to emerge from a new user of the software. Chances are, there is a nearly identical user, one how follows the same daily routine and who is trying to solve the exact same problems. But they accomplish their goals using an entirely different suite of software than someone who has set out to do the same thing. How can there possibly be so many ways to solve the same problem? Or perhaps its not as much about the finish line as it is about taste. If you think about using computers for entertainment value ? movies, games, and so on ? there is a completely different set of rationales. Here, as users, we're not thinking about how to stream content so that it has a minimal impact on others streaming the same content. That's a development perspective of someone working at the media company delivering the content. The user looking for entertainment value is looking at the content. But also the controls that allow them to manipulate the content ? changing the channel, setting preferences and bookmarks.

If I were to sit down with one of my friends and compare preferences for media on our computers, there are bound to be some similarities, but also some important contrasts. The funny thing is, I could probably track backward through time and see how our preferences diverged. It once again comes down to user class. Or in this case, each of our multiple user classes. I don't think each user around the globe can safely fit in one class of user anymore. I think most of us are wearing multiple hats. Especially if you're making a living working with computers professionally. Here, you're likely to have multiple classes applied to your user profile due to your separation of business life and personal entertainment. And, depending on what you do professionally, your profile may require more classes still to fully capture the complexity of your experience. All this leads me to believe that there is a feedback mechanism in play here. Developing a class definition for a user and applying it to someone isn't as clear cut as saying that they've used this particular type of software for so long and therefore fall under this tree. I think it's a combination of choices they've made early on as a user, what led them to make those choices, and once they've established themselves with a base user class, the process repeats itself. Only as life with computers goes one, the less significant your decisions become. At this point, the choices the user makes are an exercise in fine-tuning.

Early in a person's life with computers, they're exposed to the notion of free software, or, open source software. It isn't likely that they'll make the distinction between free and open source just yet, but that's not important. What matters is that fact that some users make the mental leap to understand that there is software available for use, free of charge, that can likely solve any of your problems. Of course, every individual use case is unique and it isn't fair to say that paying for software is never the better option ? because a lot of the time it is. What is essential, is that users understand the distinction early on in life. It's important to understand where open source is the better choice and how to go about using it. It'll set the cost expectations not only for yourself, but for newer generations that you help along the way. Given that many open source projects are fairly mainstream ? you can use Linux for 100% entertainment value ? it's more accessible these days. And if it's more accessible, the more likely users of open source technology are likely to understand the motivations of the developers that created it. And that's a valuable lesson to someone new with software.

So if understanding the full spectrum of software ? both paid proprietary and free open source ? is there a bad thing that we should avoid in early computer usage? The only thing I can think of is never take anything as a given. Especially if you're teaching kids to use computers. I think once you've established a trustful attitude toward software you've never used before, you set the bar low in terms of what you can get out of the software. Learn how to poke holes in the walls and see if the code starts pouring out. I think having this ability will help you detach software quality from branding and ultimately lead more informed life with computers.

Source: http://www.boduch.ca/2012/10/new-computer-users.html

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Video: Maria's Observation: 8 Million Without Power

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Source: http://video.msnbc.msn.com/cnbc/49615181/

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Chicago's Cook County drops bullet tax, but keeps gun levy

CHICAGO (Reuters) - The top executive of the county that includes Chicago on Wednesday dropped a proposed tax on bullets but kept a plan to tax firearms to help defray healthcare expenses associated with the high rate of gun violence.

Cook County Board President Toni Preckwinkle dropped a proposed tax of 5 cents a bullet because the tax in some cases would have been more than the ammunition price itself.

If approved by the board, the nation's third most populous county could be the first major U.S. metropolitan area to impose a tax as a form of gun control, according to the Law Center to Prevent Gun Violence.

"It is very important to us to tax guns because we know that guns are the sources of the incredible violence we have in our neighborhoods," said Preckwinkle at a news conference on Wednesday. She said 29 percent of the guns used in crimes in Chicago were purchased legally in suburban Cook County.

There have been 440 murders in Chicago so far this year, surpassing the total in all of last year - 435 - and 22.2 percent more than the same period a year ago, according to Chicago Police.

Under the plan, the County would impose a $25 tax on the purchase of firearms. The tax is expected to raise $600,000 in revenue in 2013.

Preckwinkle also proposed dedicating $2 million toward a violence prevention program, which would primarily provide grants to non-profit organizations with proven experience in violence prevention or community outreach.

She noted that 670 victims of gun violence were treated by the county's health system last year, at the average cost of $52,000 per patient.

The Cook County Board of Commissioners will vote on the firearm tax proposal on Friday. Commissioner Jesus Garcia, who supports the revised plan, said he thinks it will be approved.

Taxes on buyers or sellers of guns and/or ammunition have been proposed but failed in six states, including California, Louisiana, Massachusetts, New Jersey, Oklahoma and Pennsylvania, according to the Law Center to Prevent Gun Violence.

Tennessee has a hunting-related, 10-cents tax on shotgun shells and cartridges which applies to sellers. The money is used to support wildlife resources.

Richard Pearson, executive director of the Illinois State Rifle Association, was not immediately available for comment on the revised proposal. He had called the original proposal one of a string of "schemes" to punish law-abiding firearm owners and dealers.

Father Michael Pfleger, pastor of Chicago's St. Sabina Church, says the tax will make a difference, just as cigarette taxes affected cigarette consumption. He called gun violence "the undeclared disaster," and noted that in his crime-troubled South Side neighborhood a gun can be bought for as little as $20.

"We are a city with more guns than computers in many neighborhoods and that's unacceptable," Pfleger said.

(Reporting By Mary Wisniewski; Editing by Greg McCune and Mohammad Zargham)

Source: http://news.yahoo.com/chicagos-cook-county-drops-bullet-tax-keeps-gun-190721741.html

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The Enzo Ferrari Story

The Enzo Ferrari Story

It's mid winter, northern Italy, February 1898, and it is snowing heavily. Heavily enough, in fact, to prevent one young couple in the area from officially recording the birth of their son until two days after the event, on 20 February after his actual birth on the 18th - so forever after, 20 February 1898 would always be quoted as his birth date. And as it would turn out, that would become typical of the new arrival's relationship with authority and convention almost throughout his life, when he never seemed to have much time for doing things the 'ordinary' way. Because Enzo Anselmo Ferrari, as the boy was officially registered at two days old, would achieve great things, but rarely by working to the book.

The family lived on the outskirts of Modena, where Enzo's father, Alfredo, ran a small but busy metalworking business that, for most of the time, gave the family a fairly comfortable lifestyle. Enzo had an older brother, also called Alfredo, who was two years his senior. They shared many things, including a bedroom when they were young, and a love of homing pigeons, but in one respect they were quite different, and with a surprising twist. Alfredo senior would have liked both boys to follow in his footsteps and become engineers, but while young Alfredo accepted the idea and studied diligently, Enzo (who would become synonymous with some of the most exotic automobile engineering in the world) never showed the remotest interest in formal engineering training, or to be honest in a formal education at all.

At school he was far more interested in sports than in academic subjects, and he fulfilled one of his childhood career ambitions by briefly writing local football match reports for the prestigious newspaper Gazzetta dello Sport. But he grew out of an even bigger ambition, to become an opera singer, and in September 1908, he switched ideas again, after his father had taken him to nearby Bologna where he saw Felice Nazzaro's FIAT winning the Coppa Florio road race. Now, the ten-year-old Enzo Ferrari wanted to be a racing driver.

He had already had contact with cars, at a time when they were still rare in rural Italy where the family lived. His father owned one, and had started to service and repair cars for other owners in his workshops. And in his early teens, Enzo himself began to learn how to drive. How little did he know then that there was going to be such a famous marque of sportscars known as Ferrari, and would go on to world recognition on the road and on the racetrack.

At the same time, Enzo Ferrari was being forced to grow up very quickly. In 1914, World War I broke out; and in 1916, within months of each other, Enzo's father and brother both died - his father from pneumonia, his brother from an illness contracted during military service. In 1917, Enzo followed him into the army, and was assigned to be a blacksmith, shoeing horses. Like father and older brother, though, he suffered illnesses, and after a round of operations and hospital stays he was discharged in 1918, with what looked like poor prospects for the immediate future.

The family business had died with his father and brother, he had no real qualifications, and there were very few jobs on offer. He found one, though, and with a motoring connection - driving refurbished ex-military light vehicle chassis between Turin and Milan, for a Bolognese engineer who had started a business rebodying them for the civilian market. And it was through this apparently mundane driving job that Enzo Ferrari moved a step closer to that still burning motor sporting ambition. History would show how he fulfilled his dreams with the number of Ferrari sales that have been acheived since that time. The world just wouldn't be the same without the prancing horse.

Source: http://www.streetarticles.com/automotive/the-enzo-ferrari-story

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News Summary: Pandora refreshes apps

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Deluxe Carpet Flooring at St Paul | Home Improvement

Moving to a new home, both the newly built home and the old one, will require you to check the condition. A few adjustments and sometimes even renovations will be needed in order to acquire the desired home?s atmosphere. The important parts should be at the best condition and you can also add some personalization during the adjustments process to make everything more comfortable for you.

Home flooring is one of the most crucial parts at your home that should be kept at the best condition. Even if you have got a nice hard flooring at your home, sometimes you need to add carpets or laminating layer for aesthetic needs. St Paul flooring from Deluxecarpetflooringamerica.com will be able to handle all of your flooring needs with their good reputation and experience in dealing with different flooring requirements of many homeowners.

Even if you are clueless about what to do with your current flooring, the articles and recommendation at the website will be able to help you make the right decision. Since remodelling the flooring will require quite a lot of money, make sure you are making the right choice with the reliable guide provided by this website. Just take a while to look around and you will be inspired with great flooring ideas to be applied at your home.

Source: http://www.hawkeyevillage.com/deluxe-carpet-flooring-at-st-paul

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Romney on the Stump (TIME)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/259125682?client_source=feed&format=rss

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New way to prevent recurrent ear infections?

ScienceDaily (Oct. 30, 2012) ? Eliminating bacteria's DNA and boosting antimicrobial proteins that already exist may help prevent middle ear infections from reoccurring. These are the findings from a Nationwide Children's Hospital study that examined how an immune defense protein common in the middle ear interacts with a structure meant to protect a colony of bacteria.

The bacterium nontypeable Haemophilus influenzae (NTHI) causes a wide range of diseases of both the lower and upper airways, including middle ear infection. NTHI, like most other bacteria, can form a biofilm, a robust community of bacteria that allows the bacteria to evade the host's immune system and protects the bacteria from antibiotics and other therapies designed to kill them.

Human beta-defensin-3 is an antimicrobial defense protein expressed in the middle ear of humans and other mammals that kills both Gram-positive and Gram-negative bacteria. Previous research has shown that if expression of beta-defensin is disrupted, the host's ability to control the bacteria in the upper airway is altered and infection worsens.

Investigators in The Research Institute at Nationwide Children's Hospital hypothesized that human beta-defensin-3 might lose its power to kill NTHI if it got caught up within the extracellular DNA that makes up a biofilm's outer layer, thus preventing its contact with bacteria within the biofilm.

"Antimicrobial host defense proteins, like human beta-defensin-3, have been shown to bind to non-host DNA," says Lauren O. Bakaletz, PhD director of the Center for Microbial Pathogenesis "This interaction has an impact on the defense protein's ability to function."

Upon examining their animal model of middle ear infection, Dr. Bakaletz' team found that bacterial DNA and the animal's defense peptides were detected together in biofilms that developed during infection. Also, the defense peptide was predominantly co-localized with the biofilm's extracellular DNA.

When the team exposed the bacteria that cause ear infections to a concentration of human-beta defensin-3 that is typically detected in the a middle ear of a child with active infection, the peptide was able to kill 100 percent of the NTHI, but the killing stopped when extracellular DNA was introduced to the reaction.

"These data support the conclusion that the killing activity of the antimicrobial defense protein was decreased in an NTHI-induced biofilm due to its interaction with eDNA," says Dr. Bakaletz, who is the lead study author and professor of Pediatrics and Otolaryngology at The Ohio State University College of Medicine.

When they removed extracellular DNA from the biofilm, the killing activity of the defense peptide was rescued.

"The ability to restore antimicrobial defense protein activity is encouraging, since biofilms are resistant to most treatments, including traditional antibiotics," says Dr. Bakaletz.

Dr. Bakaletz says this study provides evidence for a new treatment regimen to target biofilms formed by NTHI during middle ear infection. One approach would be to deliver a therapeutic agent that can disrupt bacterial DNA, in conjunction with human beta-defensin-3 to the middle ear of a child with chronic, recurrent infection. Physicians could follow the same pathway used to target the middle ear during ear tube surgery, a common treatment for chronic ear infections.

"This approach would likely bolster the ability of the innate immune system to manage NTHI-induced biofilms, avoiding the need for antibiotics or empowering the use of antibiotics we already have in our arsenal," says Dr. Bakaletz. "Doing so could help diminish the recurrent nature of middle ear infection."

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Story Source:

The above story is reprinted from materials provided by Nationwide Children's Hospital, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Eric A. Jones, Glen McGillivary, Lauren O. Bakaletz. Extracellular DNA within a Nontypeable Haemophilus influenzae-Induced Biofilm Binds Human Beta Defensin-3 and Reduces Its Antimicrobial Activity. Journal of Innate Immunity, 2012; DOI: 10.1159/000339961

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/8r4rBgRgauc/121030101340.htm

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What Lies Beneath the Surface Tablet's Screen

The last thing people probably consider when buying a new gizmo or gadget is how hard it might be to fix, but according to the teardown team at iFixit, Microsoft's shiny new Surface tablet is easier to repair than the latest iPad, but it is still difficult to take apart. The online teardown site rated the Surface's "repairability" a 4 on a scale of 1 to 10, with 10 being the easiest.


Source: http://ectnews.com.feedsportal.com/c/34520/f/632000/s/2502ee57/l/0L0Stechnewsworld0N0Crsstory0C7650A0A0Bhtml/story01.htm

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Learning about and Working out WordPress for Your Web Site ...

WordPress is a cutting edge publishing platform with a focus on looks, internet criteria, and usability, and it can easily be made use of to create easy blog sites and complicated website. Plus, there are tons of free of charge WordPress design templates available on the web, so you don?t should be an internet designer or developer to create a lovely and practical internet site. WordPress is both free of charge and valuable at the same time.

WordPress is exceptionally user-friendly, so it?s a wonderful content management system (CMS) for beginners. WordPress hosting first got its start as a blogging platform, and many individuals still wrongly think it can easily not be made use of as a CMS. Nonetheless, WordPress has grown so much over the past couple of years, that tons of people are using it to create easy blog sites, professional sites, as well as online stores!

If you don?t have a great deal of technical understanding, then we definitely advise using WordPress for your internet site or blog site. There are tons of free of charge and exceptional plugins available for WordPress, so you can easily customise your site to fulfill your requirements. Nonetheless, you may want to be careful about making a great deal of modifications to WordPress, as these alterations may cause your site to break when you upgrade to the most recent variation (and you must constantly keep your installation up to date, since it helps avoid your site from being hacked).

In reality, a great deal of developers dislike using WordPress for this specific explanation: they make tons of cool modifications to a WordPress. site, then they upgrade to the most recent variation, and frequentlies the site breaks or their changes vanish. If you?re a beginner, then we don?t advise using a great deal of plugins to customize your WordPress site till you have actually gotten a lot more technical understanding. WordPress has a huge and active community of developers and users to help you out, so we definitely advise having a look at their official internet site and online forums when you?re having difficulty or you just want to discover even more about this CMS.

Compared with other content management systems like Drupal and Joomla, we think WordPress has the widest variety of attractive free of charge and exceptional themes. You can easily locate some fantastic themes for almost every kind of blog site or internet site you can easily envision, and we actually advise using the themes available on ThemeForest.

In addition to blog sites and sites, you can easily additionally make use of WordPress to create an on-line store thanks to numerous ecommerce WordPress plugins. The charm of WordPress is in its simplicity, and we don?t think it is complicated enough for running a huge online store, nor must it be.

WordPress is an extremely user-friendly piece of software, making it fast and simple to discover, and there are some providers that specialise in WordPress hosting. WordPress calls for at least one database, so be sure to take this into consideration when you pick a hosting plan for your internet site or blog site.

Sadly, due to its appeal, WordPress is commonly targeted by hackers, so it?s exceptionally crucial for users to keep the application and plugins up-to-date. In addition to running the most recent variation of WordPress and various plugins, users should pick tough usernames and passwords to help keep their sites secure.

You may want to be careful about making a great deal of modifications to WordPress, as these alterations may cause your site to break when you upgrade to the latest variation (and you must constantly keep your installation up to date, since it helps avoid your site from being hacked).

A whole lot of developers dislike using WordPress for this specific explanation: they make tons of cool modifications to a WordPress site, then they upgrade to the latest variation, and commonly times the site breaks or their changes vanish. In addition to blog sites and sites, you can easily additionally make use of WordPress to create an on-line store thanks to numerous ecommerce WordPress plugins. WordPress is an extremely user-friendly piece of software, making it fast and simple to discover, and there are some providers that specialise in WordPress.

Source: http://www.unhas.ac.id/fardin/?p=702

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Tuesday, October 30, 2012

Pub Rants: And Speaking Of Money - Our Next Webinar - The ...

STATUS: Not much has changed from last post?.

What?s playing on the XM or iPod right now?? CRASH INTO ME By Stevie Nicks

And since we are speaking of money and concerns over the possibly shrinking advances, LOL, this leads right into my very next webinar that's taking place on Wednesday, Nov. 7, 2012 from 6 to 8 pm Mountain time. It's called SHOW ME THE MONEY: The Anatomy of $ In A Book Deal.

I'm literally doing a 2-hour workshop that walks writers through a publishing contract and the anatomy of money in it. I'm using actual contract clauses to illustrate how and what earns a writer money in a publishing agreement.

I'm pretty sure this will be the best tutorial you'll have without actually having a book deal and your own agent walking you through your brand spankin' new contract.

"A little learning is a dangerous thing" as Alexander Pope says but I'm of the philosophy that you can't learn less.? I like to be as thoroughly educated as I possibly can before being confronted with something.

Stuff you'll learn:

1) What can a writer earn in terms of advances for different genres?
2) What are the standard royalties? Royalty escalators?
3) What is "high discount" and how can it impact what you earn?
4) Bonus clauses. What are they? What types can be built into a contract?
5) What subsidiary rights can be sold and what are typical monies involved.
6) Clauses that don't immediately seem to be about money but can impact what you earn anyway.

Sound like something you might want to know? Then I'll see you there.

Source: http://pubrants.blogspot.com/2012/10/and-speaking-of-money-our-next-webinar.html

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Blog Archive ? I Love You ? Why? Making Romantic Relationships ...

The final installment of this 4-part series on believable romantic relationships: does the audience care if they get together in the end?

In the first three parts, I discussed the importance of the relationship being between two characters with compatible characteristics.? They must have mutually attractive traits that make the audience believe they are a perfect match.? Secondly, the obstacles they face must be realistic according to the rules of the world in which they live.? The crazier the world, the crazier the obstacle.? Thirdly, this obstacle must be one which can be overcome without a doubt that it will ever resurface in the future.

You could write a love story that has all these elements and still the audience may not care if they get together in the end.? So what makes us care?

?

Likability

It?s one thing for the characters to like one another, but it?s also just as important that the audience likes them too.? Blake Snyder?s book Save the Cat is so titled because he believes that your protagonist must do something kind early on to make him immediately likable to the audience.? Once you establish your characters? good side, they can go on to do all sorts of horrible things and we?ll forgive them and still root for them because we know they?re not all bad.

Likability is two-fold:

  1. Character likability ? does the audience find each character likable
  2. Relationship likability ? does the audience like how these two are together as a couple

Lose A Guy.? In the opening scene, Andie rushes off to save her friend Michelle when she doesn?t come into work after another bad breakup.? Andie says a lot of wonderful things about Michelle and even protects her from having her personal life exposed by offering to do the article on How to Lose A Guy.? Ben is pretty unsympathetic in his first few scenes, but we see women find him sexy and his coworkers like him so there must be something nice about him.? He doesn?t seem like a total jerk, but he seems cocky and manipulative.? He swoops in on a business meeting to steal the Lauer Diamond account, yet once he states his case, you kind of like him for his confidence but you also kind of hate him because he doesn?t pause to consider the consequences of manipulating a woman to fall in love with him.? Then as he charms Andie, you really like him, but more importantly, you like the two of them together.? As the film progresses, there are several scenes showing how great these two are together and when you see Andie truly fall in love with Ben at his parents? house, you can?t help but fall in love with them too.

Harry & Sally.? In the opening scene, Harry?s making out with his girlfriend.? He seems kind and genuine because he tells her he loves her and he?ll call her soon and that he already misses her.? Sally honks the horn to interrupt them kissing, which is rude, but funny and then smiles and apologizes, which makes her likeable.? But then we see his crassness and so-called dark side, which is really just pessimism.? And Sally comes off as uptight and pragmatic.? Their flaws are funny and realistic, which makes them likable especially when they spar with one another because of them.? Over the span of the next several years, these two grow into more mature adults and their neuroses are not as prominent, but also because Harry and Sally come to appreciate them, the audience does too.

Friends with Benefits.? Both characters are immediately likable as they?re smart, funny and vulnerable.? It makes sense these two would stay away from each other to avoid heartbreak after getting dumped and audiences can relate to that.?? These two are great together because they?re fun, witty, playful and don?t take their relationship too seriously.? They challenge one another and they?re best friends.? By the time Dylan does the douchebag thing and uses Jamie?s weakness as a reason not to be with her, we hate him for it but understand why he said it: he loves her, but is too afraid to admit it.? So we forgive him right away and it makes us really want him to go after her and apologize.

Legally Blonde.? In the beginning, it?s a little hard to like Elle because she?s so superficial so we can see why Warner dumped her.? Yet it?s because he dumps her when she?s expecting a proposal that we feel sorry for her and resent Warner for hurting her especially in such a shallow way.? Once Elle decides to win him back by going to law school at of all places, Harvard, you can?t help but admire her gumption.? You want Elle to get her way, but you kind of don?t want Warner to win.? Because everyone else is horrible to her especially Warner?s new fiancee, Warner doesn?t seem so awful and Elle?s sweetness shines through.? As Elle matures and realizes her worth, we want Elle to see she?s better than Warner and to end up with someone who appreciates her for who she is, like Emmett.

?

Unlikability

What happens when two characters and their relationship is unlikable?? Sometimes films rely so heavily on the charm and appeal of the actors playing the parts that they forget to make them likable.? When characters are too horrible for too long and horrible to one another, there?s nothing to root for even when they do ultimately become better people and fall in love.? This isn?t to say you can?t have a love story between two unlikable characters and make it work.? Characters can be largely unlikable, but not so horrible that there?s no humanity or vulnerability in them.

The Proposal.? When we first meet Andrew we like him simply because he cares if he?s late for work and profusely thanks the Starbucks girl by name when she has his coffees ready.? Yet once he?s in the office, he?s not so nice: he calls the receptionist ?Captain Obvious? for telling him he?s late then yells at the mail guy for bumping into him causing him to spill his coffees.? Margaret, however, is immediately unlikable.? As she enters the office, everyone avoids her.? She?s a bitch, she talks about people as if they?re wasting her time and can?t accept a compliment, then fires someone, and threatens her assistant into marrying her, not caring how it affects his life.? It?s not until about an hour into the film that you see her softer side and actually start to like her, but it might come a bit too late.? Andrew begins to see why she is such a heartless bitch and develops a soft spot for her, so we do too.? He also pushes her around for a change, which she needs and deserves, but it doesn?t necessarily make us like them together as a couple.? They?re supposedly good together because he?s the only one who can stand up to her and the only one she opened up to, but it doesn?t quite work.

If we had a glimpse into Margaret?s vulnerable side before she ?proposes? to Andrew, we?d understand why she was such a cold-hearted bitch and it would have made us want her to break down her defenses to find love.? Margaret didn?t have any friends or family so she did everything herself and has become very successful, but we didn?t see how she felt about it.? If she felt lonely or longed for a relationship or had at least one friend, it would have made her more human.? I guess the idea was that she didn?t think about it, which was why she was able to ?propose? without considering the consequences.? But because we later see she does have a heart and is capable of letting it show, she must have the capacity to think about other people.? She?s human so she must think about relationships, must be attracted to men even if it?s just for sex, but we have no idea how she feels about any of this.? If she closed herself off to love for a reason, it would have helped to know this up front.

It would have helped too to know something about Andrew?s romantic life before the ?proposal?.? He?s too busy to have a girlfriend or even show interest in dating, which is obvious when he doesn?t flirt with the cute girl at Starbucks, but we should at least know how he feels about marriage or that he left someone behind in Alaska to pursue his dream.? Then we?d know what a great sacrifice it was for him to marry someone he didn?t love at the moment she ?proposes?.


Source: http://www.writeforhollywood.com/i-love-you-why-making-romantic-relationships-believable-part-4-of-4/

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Camaro Hot Wheels and a roundup of today's car news

Chevrolet's Camaro gets a special appearance edition in the form of the Hot Wheels Edition, Ireson writes. The Hot Wheels upgrade costs?$6,995 and is available on any standard Camaro or Camaro Convertible.

By Nelson Ireson,?Guest blogger / October 29, 2012

General Motors Vice President of Global Design Ed Welburn unveils the 2012 Chevrolet Camaro ZL1 -- the fastest Camaro ever offered by Chevrolet --at the Chicago Auto Show in this February 2011 file photo. Chevrolet's Camaro is getting a special Hot Wheels Edition, Ireson writes.

Tyler Mallory/Chevrolet/Reuters/Handout

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BMW has launched a new Frozen Limited Edition of the 2013 M3?Coupe, and it wears a special Frozen pain finish in a range of colors, as well as getting the Competition Package and other goodies.

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This website offers the?best car news, photos, spy shots, and auto-show coverage. Click here?for car news?from around the world ? and around the clock.

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Chevrolet's Camaro also gets a special appearance edition, in the form of the Hot Wheels Edition, a $6,995 package upgrade on any standard Camaro or Camaro Convertible--which can be ordered from your dealer. The?car?will make its debut at SEMA this week.

And Lexus is also bringing a car to SEMA, but this time it's not just about looks: Lexus is adding a supercharger to the GS 350 F Sport. Yes, it sounds like fun to us, too.?

Al-Qaida claims deadly holiday attacks in Iraq

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Video: Storm winds pick up on East Coast



>> thank you. all day sandy has been lashing north carolina 's outer banks . julie martin is in nags head for us tonight. julie?

>> reporter: we have been taking a beating all day long here along the outer banks , the tropical storm force wind gusts started around midnight and they really haven't let up, that plus the stinging rain showers coming in has made for a miserable existence all along the outer banks , and sandy is well offshore a couple of hundred miles is a testment to the size and strength of this storm. many are chosen to stay and ride this house. nonetheless, they have had their share of problems with this, we have seen flooded roadways, highway 95 completely impassable due to coastal flooding, and we have seen some power outages with that

Source: http://video.msnbc.msn.com/nightly-news/49590370/

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#1377| Weirdos in Print! : jemmawei

Posted on Monday, October 29, 2012 ? Leave a Comment?

I don?t know if you guys remember, but to me there?s no name with a memorable ring quite like the weirods. I?m not too sure how my ancestors will take to the nickname, but it seems like it stuck ever since i first mentioned it. In any case, i got sidetracked- what i was trying to talk about was the home without walls singtel virtual scrapbook initiative i blogged about awhile back.

Not limited to the virtual realm now- because last week i received a hard copy of my scrapbook, and it?s absolutely gorgeous! Check it out:

It?s literally identical to what I crafted online! Such a perfect conversation point for dinners and a great way for guests to get acquainted with our family history..

Yup, that?s what im talking about.

It arrived when i was asleep so i woke up to a pretty lovely surprise, flipping through the scrapbook i painstakingly crafted (ok not as painstakingly as if i had done it in real life because, you know, superglue, but it took me pretty long too ok). Honestly, it just feels so sleek, and it looks great just sitting there on our coffee table. A few more shots of it:



everyone at home is really impressed by it, except my second sister who is protesting quite strongly at being immortalized in print as ?the strange one?. But you know what they say- you give some and you take some.

The competition to win a printed copy has since ended, but you can still create your own virtual scrapbook to share with your family and friends online here :)

You can also get your dose of warm fuzzy feelings at the Singtel home without walls photo gallery- it consists a series of fantastic, fantastic, heartfelt photos taken by singaporeans all over the island and submitted with personal stories attached. Such a wonderful initiative by Singtel- what with all the rush forward for progress and moving upwards and onwards, it?s so heartwarming to know that people everywhere still flock to proudly express their love for their family :?)

This post is starting to turn very cheesy- but for all the right reasons. Have a great start to the week you guys, and happy monday morning to you too.

x
?jem

Source: http://jemmawei.com/2012/10/29/1377-weirdos-in-print/

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How to make furikake | Vegan | Gluten-free - Recipe Renovator

Bowl of furikakeHere is the how-to I promised to make your own delicious furikake, a Japanese topping for rice and stir-fries. I used it here in this unprocessed breakfast of brown rice, toasted sesame oil, and furikake. This topping, once made, will last you for months, and it?s low in sodium, high in minerals and nutrients, and totally savory-licious.

I use only organic vegetables for this, and dry them in my dehydrator. If you don?t have a dehydrator you can dry them in your oven set on the lowest possible setting until they are crispy and completely dry. If you don?t wish to do that, some stores carry pre-dried veggie as snacks and you could use those.

Furikake
Makes about 1-1/2 cups

1 yellow bell pepper
2 carrots
1 small zucchini
6 T. (55 g) sesame seeds (black, tan, or a mixture of the two)
1/2 t. (1 g) sea salt, optional
3 sheets of nori (sold in packages for rolling sushi)

Wash and dry the vegetables and remove the tops, cores, seeds, etc.

Cut them into thin strips using a mandoline or sharp knife, and lay the strips on the dehydrator trays or on top of parchment-lined baking sheets if using an oven. Dry at 135F/60C overnight or until crispy. Everything must be completely dry or it will mold.Dried vegetables for furikakePut the veggies in the food processor and pulse until finely minced.

When the veggies are ready, rinse the sesame seeds and drain using a fine mesh strainer. Toast them in a dry skillet until they puff up and you can smell their aroma, stirring occasionally. They should crush easily between your fingers.

Mix the sesame seeds, optional salt, and vegetables together.

Toast the nori sheets over a low burner (electric or gas) by waving them back and forth until they darken and become stiff and crispy. This takes about a minute.Cutting the nori into strips for furikakeCut the nori into thin strips, then into the smallest pieces you can, or crumble with your fingers into the bowl. Mix well, then place in a glass jar. If you have a packet of dessicant from another food package, add it to the jar to keep the furikake dry and fresh.

Notes: Do NOT try to break up the nori with the food processor. It breaks down and makes a green ring that is nearly impossible to remove. I don?t add the salt, as I nearly always use furikake with tamari or Bragg?s which is plenty salty on its own.

All of our recipes are gluten-free, sugar-free, and made with plant-based ingredients to help you build a healthy life. We support Meatless Monday. Look for midweek essays and Friday how-to and giveaways (when available).

If you?ve thought about getting a dehydrator, this is very similar to the one I have and it?s not very expensive at all. You can also buy more trays as needed, which is a handy option.

Source: http://reciperenovator.com/healthyrecipes/glutenfree/how-to-make-furikake-dried-seaweed-sesame-vegetable-topping/

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Small earthquake rattles Southern California

By NBC News staff and news services

Updated at 4:26 p.m. ET: A small earthquake rattled Southern California on Sunday morning, causing?buildings?to shake in downtown Los Angeles.?There were no immediate reports of damage or injury. ??

The quake had a preliminary magnitude of 3.9 magnitude and struck at 8:24 a.m., ?the U.S. Geological Survey said. It was centered about 5 miles east-southeast of Santa Clarita, and about?24 miles north-northwest of downtown Los Angeles.?

It may not have been a hurricane, but an earthquake and tsunami warning worried state agencies along the West Coast. NBC's Miguel Almaguer reports.

Shaking was felt across the Santa Clarita Valley, in downtown Los Angeles, in West Hollywood and along LA County beaches, The Associated Press reported.

The quake was followed by several smaller aftershocks.

A sheriff's dispatcher in Santa Clarita told the AP ?there were no calls reporting damage or injury.

More content from NBCNews.com:

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Source: http://usnews.nbcnews.com/_news/2012/10/28/14758265-small-earthquake-rattles-southern-california-buildings-shake-in-los-angeles?lite

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The Microsoft Windows Phone 8 event happens tomorrow, get your liveblog here!

The Microsoft Windows Phone 8 event happens tomorrow, get your liveblog here!

We know tomorrow's Windows Phone 8 event will finally answer all of those burning mysteries that we've been yearning to hear more about since Microsoft first announced the new OS in June. After all, the company has kept its upcoming platform under tight wraps, preventing its hardware partners from showing it off to the press. So what else will the folks from Redmond have up their sleeves? Stay tuned here as we bring you all of the revelations live in San Francisco, tomorrow at 1PM ET!

October 29, 2012 1:00 PM EDT

Filed under: , ,

The Microsoft Windows Phone 8 event happens tomorrow, get your liveblog here! originally appeared on Engadget on Sun, 28 Oct 2012 23:30:00 EDT. Please see our terms for use of feeds.

Permalink   |   | Email this | Comments

Source: http://www.engadget.com/2012/10/28/microsoft-windows-phone-8-event/

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Windows 8 Pro Upgrade ? $14.99

Did you know that if you purchase(d) a Microsoft Windows 7 notebook or desktop between ?June 2, 2012 and January 31, 2013 then you may be eligible for a Windows 8 Pro upgrade for $14.99? The offer is for customers (e.g. home users, students, and enthusiasts) who purchase a qualified PC. A qualified PC is [...]

Source: http://the-gadgeteer.com/2012/10/28/windows-8-pro-upgrade-14-99/

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Northborough Self Improvement Expert Launches Life Coaching ...

Northborough, MA (PRWEB) October 28, 2012

Chris Chaves has launched the areas first fitness facility with the goal of educating local residents on how to set and achieve lofty goals without having to be dependent on a Personal Trainer the rest of their lives.

Using his Guided Step Coaching approach, which is a unique blend of Professional Coaching, Personal Training and Nutritional Consulting, Chris is able to empower his clients to gradually adopt lifestyle changes that build momentum and create lasting results.

Chris recognized early on that many people try to get healthier through diet or exercise but the majority do not achieve lasting results for two main reasons:

1.

Source: http://www.littleleaguebaseballinfo.net/northborough-self-improvement-expert-launches-life-coaching-and-personal-training-studio-at-nicholas-michaels-spa/

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Scientists decode 'software' instructions of aggressive leukemia cells

ScienceDaily (Oct. 29, 2012) ? A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

The research, published in Cancer Discovery, is the first study to show how these three different forms of white blood cell cancer are epigenetically programmed by several different molecules controlling cascading biological networks that manipulate normal gene function, directing cancer development and growth.

"Epigenetic programming is the software that is written on to human DNA, which can be viewed as its hard drive. This programming contains the instructions that determine how cells including leukemia cells function and cause disease," says the study's lead investigator, Dr. Ari Melnick, associate professor of medicine and director of the Raymond and Beverly Sackler Center for Biomedical and Physical Sciences at Weill Cornell Medical College.

"Finding the instructions that ultimately lead to cancer development, and to the especially bad outcome seen in patients with these different forms of ALL, is especially urgent. Epigenetic instructions are contained in many chemical layers. Our study is the first to integrate the decoding of many layers simultaneously, which has enabled us to unlock some of the mysteries explaining the malignant and aggressive behavior of these leukemias," says Dr. Melnick, who is also a hematologist-oncologist at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

Abnormal Epigenetic Programming Leads to Poor Outcomes

The research team examined abnormalities in the "software" epigenetic programming that leads to the three forms of adult B-acute lymphoblastic leukemia (B-ALL), the most common form of ALL. These forms are BCR-ABL1-positive B-ALL, E2A-PBX1-positive B-ALL, and MLLr-B-ALL. These three B-ALL subtypes feature mutations of different master regulatory genes which force bone marrow cells to produce cancer-promoting proteins. Long-term survival is less than 40 percent among these patients.

"Similar to normal tissue, we believe that tumors may be dependent on specific patterns of epigenetic programming -- especially in B-ALL, where studies suggests epigenomic programming is globally disrupted," Dr. Melnick says. "Our goal was to identify epigenetically modified genes and the molecular machines that cause them to become abnormally programmed."

To that end, the research team performed DNA methylation and gene expression profiling on 215 adult B-ALL patients enrolled in the ECOG E2993 clinical trial, a multi-center and multi-national study, testing different forms of treatment in patients with ALL.

Researchers identified core epigenetic gene signatures that were associated with abnormal fusion proteins. In the case of BCR-ABL1-positive B-ALL, they found that the most deregulated gene network centered around an extraordinarily epigenetically deregulated gene they identified as interleukin-2 receptor alpha, which encodes a protein called CD25.

"Among patients who had BCR-ABL1-positive B-ALL, it was those with aberrant epigenetic programming of CD25 that had significantly worse outcome," says Dr. Melnick. "It's the patients that have this programming glitch that do really poorly."

Although the researchers don't yet know what CD25 does, and why it is important, they say CD25 will be a useful biomarker to test for patients that are at highest risk for poorer outcome.

Dr. Melnick stresses that therapeutic antibodies to the CD25 protein already exist that can, theoretically, destroy leukemic cells expressing this protein. The research team showed that using the CD25 antibody successfully killed BCR-ABL1-positive B-ALL in laboratory experiments. "One could potentially conceive of a human clinical trial where those antibodies are used to attack these cancerous cells," he says.

Researchers also discovered what is writing the bad software in the other two B-ALL subtypes. In both cases, the abnormal cancer proteins E2A-PBX1 and MLLr turn out to be directly involved in altering the epigenetic programming of leukemic cells. Remarkably, MLLr epigenetically turns on a powerful cancer protein called BCL6. In the study, drugs developed by Dr. Melnick that block BCL6 activity potently killed and suppressed the ALL cells in patients enrolled in this clinical trial, which warrants the testing of BCL6 inhibitors in this aggressive form of ALL.

"This study links the direct actions of oncogenic fusion proteins with disruption of epigenetic regulation that leads to abnormal production of cancer-driving genes," Dr. Melnick says. "It potentially provides us with a biomarker for cancer outcomes as well as potential treatments in these aggressive forms of leukemia."

This research study was supported by the Chemotherapy Foundation, Burroughs Wellcome Foundation, The Leukemia & Lymphoma Society and the Sackler Center for Biomedical and Physical Sciences at the Weill Cornell Medical College.

Study co-authors include Dr. Sarah Brennan, Yushan Li, Dr. Chuanxin Huang, Yuan Xin, Dr. Monica L. Guzman and Dr. Olivier Elemento from Weill Cornell; Dr. Huimin Geng, formerly of Weill Cornell and now at University of California, San Francisco; Dr. Janis Racevskis and Dr. Elisabeth Paietta from Albert Einstein College of Medicine; Dr. Thomas A. Milne, Dr. Wei-Yi Chen, Dr. Debabrata Biswa, Dr. C. David Allis and Dr. Robert G. Roeder from Rockefeller University; Christian Hurtz, Dr. Soo-Mi Kweon, Dr. Seyedmehdi Shojaee and Dr. Markus M?schen from the University of Southern California, Los Angeles; Lynette Zickl and Dr. Donna Neuberg from the Dana Farber Cancer Institute, Boston; Dr. Rhett P. Ketterling and Dr. Mark R. Litzow from the Mayo Clinic, Rochester, Minnesota; Dr. Selina M. Luger from the University of Pennsylvania; Dr. Martin S. Tallman from the Memorial Sloan-Kettering Cancer Center; Dr. Jacob M. Rowe from the Rambam Medical Center in Haifa, Israel; and Dr. Hillard Lazarus from Case Western Reserve University in Cleveland, Ohio.

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The above story is reprinted from materials provided by NewYork-Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/ZjylkWo0_cI/121029103504.htm

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Monday, October 29, 2012

Cancer docs often delay referrals to hospice care

NEW YORK (Reuters Health) - Cancer doctors often refer their patients to palliative care very late in the course of disease, according to a new survey from Canada.

About a third of oncologists said they refer patients to palliative care, or hospice, when they diagnose a cancer that has spread and therefore usually is incurable.

Another third, however, said they wait until chemotherapy has been stopped, which is often just a few months or even weeks away from death.

"All palliative specialists believe that palliative care should be involved early," said Dr. Camilla Zimmermann of Princess Margaret Hospital in Toronto, who led the study with funding from the Canadian Cancer Society.

"Despite that and despite guidelines to refer early, many studies have shown that palliative still happens too late, in the last few months of life."

Rather than providing aggressive medical treatments, palliative care focuses on improving a person's well-being by offering pain management as well as psychological, social and sometimes spiritual care.

"It is basically team-based whole-person care," Zimmermann told Reuters Health. "The take-home message for me is that the palliative care specialists and oncologists need to work more in collaboration."

The new findings, published in the Journal of Clinical Oncology, are based on a survey of 603 physicians. Most of the doctors did have palliative services available to them, although some were more comprehensive than others.

In the U.S., the picture might be different. A previous survey found six out of 10 National Cancer Institute-designated centers had access to palliative clinics, whereas less than a fourth of cancer centers that didn't carry that designation had such access.

There are also differences in the insurance coverage of hospice between the U.S. and Canada. Zimmermann said patients in the U.S. cannot receive hospice benefits if they are still getting chemotherapy, which would be an obvious barrier to early referral.

However, she added, that shouldn't prevent oncologists from reaching out to palliative specialists at the hospital and make sure the transition is as smooth as possible.

"What we are trying to encourage is that everybody gets involved a bit earlier," Zimmermann told Reuters Health.

SOURCE: http://bit.ly/Phb4FH Journal of Clinical Oncology, online October 29, 2012.

Source: http://news.yahoo.com/cancer-docs-often-delay-referrals-hospice-care-210129654.html

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